Functions of the Adrenal Glands: Exam-Focused Notes

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The adrenal glands are small, triangular endocrine glands located on top of each kidney. They produce vital hormones — including cortisol, aldosterone, adrenaline, and noradrenaline — that regulate metabolism, blood pressure, stress response, immune function, and electrolyte balance.

What Are the Adrenal Glands?

  • Location: On top of each kidney
  • Shape: Small, triangular
  • System: Part of the endocrine system
  • Structure:
    • Adrenal Cortex (outer layer) – produces steroid hormones
    • Adrenal Medulla (inner layer) – produces catecholamines (adrenaline & noradrenaline)

Main Functions of the Adrenal Glands

HormoneProduced ByPrimary Function
CortisolAdrenal CortexRegulates metabolism, controls inflammation, manages stress response, and maintains blood sugar
AldosteroneAdrenal CortexControls sodium & potassium balance, regulates blood pressure
Adrenaline (Epinephrine)Adrenal MedullaIncreases heart rate, boosts energy, prepares body for “fight-or-flight”
Noradrenaline (Norepinephrine)Adrenal MedullaConstricts blood vessels, increases blood pressure, supports stress response
AndrogensAdrenal CortexContribute to sexual development and libido

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Detailed Roles in the Body

🧠 Stress Response

  • Cortisol and adrenaline help the body respond to physical or emotional stress.
  • Increase glucose availability for energy.
  • Enhance alertness and reaction speed.

⚡ Metabolism Regulation

  • Cortisol influences how the body uses fats, proteins, and carbohydrates.
  • Helps maintain steady blood sugar levels.

💧 Fluid & Electrolyte Balance

  • Aldosterone regulates sodium and potassium levels.
  • Maintains proper hydration and blood pressure.

❤️ Cardiovascular Function

  • Adrenaline and noradrenaline adjust heart rate and blood vessel tone during emergencies.

🛡️ Immune Modulation

  • Cortisol helps control inflammation and immune responses.

Common Adrenal Gland Disorders

ConditionCauseKey Symptoms
Addison’s DiseaseLow cortisol & aldosterone (autoimmune or damage)Fatigue, weight loss, low BP
Cushing’s SyndromeExcess cortisolWeight gain, high BP, muscle weakness
PheochromocytomaTumor in adrenal medullaHigh BP, rapid heartbeat, sweating
Congenital Adrenal HyperplasiaGenetic enzyme deficiencyHormonal imbalance, abnormal development

How to Keep Adrenal Glands Healthy

  • Balanced diet rich in whole foods
  • Adequate sleep to regulate cortisol cycles
  • Stress management (meditation, exercise)
  • Regular check-ups if symptoms of hormonal imbalance appear

Key Takeaways

  • The adrenal glands are vital hormone factories that keep your body’s stress, metabolism, and fluid balance in check.
  • Both overproduction and underproduction of adrenal hormones can cause serious health issues.
  • Early diagnosis and treatment of adrenal disorders can prevent complications.

References

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